About   Help   FAQ
Phenotype Image Detail
Image
Caption Intrinsic failure of Mad2l2tm1Mpz/Mad2l2tm1Mpz Tg(Prdm1-cre)1Masu/0 primordial germ cells (PGCs). Apoptosis (TUNEL assay) in E8.75 embryo sections of hindgut endoderm after the conditional knockout of Mad2l2 by Prdm1-Cre. SSEA1-expressing PGCs are marked by arrowheads. Note the apoptotic and non-apoptotic PGC in knockout section. Arrow points to an SSEA1-negative apoptotic cell in the conditional knockout section. Scale bar, 20 um.
Copyright This image is from Pirouz M, PLoS Genet 2013 Aug;9(8):e1003712, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:223048
Associated
Alleles
Symbol Name
Mad2l2tm1Mpz MAD2 mitotic arrest deficient-like 2; targeted mutation 1, Mehdi Pirouz
Tg(Prdm1-cre)1Masu transgene insertion 1, M Azim Surani
Associated
Genotypes
Allelic Composition Genetic Background
Mad2l2tm1Mpz/Mad2l2tm1Mpz
Tg(Prdm1-cre)1Masu/0
involves: 129S2/SvPas * C57BL/6 * CBA

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory