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Phenotype Image Detail
Image
Caption Limb abnormalities and edema in Tbx3tm2Moon/Tbx3tm1.1Moon (GH/N) hypomorphs. (A and D) Wild-type (+/+) (A) and mutant (D) embryos are only externally distinguishable by edema (white arrowhead) and limb abnormalities (red arrowhead). (B, C, E, and F) Skeleton preparations of mutant hypomorphs forelimbs (E) and hindlimbs (F) show duplicated first digit (forelimbs), missing posterior digits (red arrows), carpal or tarsal bones (green arrows), and the ulna or fibula (blue arrows). (Scale bars: 1 um.)
Copyright This image is from Frank DU, Proc Natl Acad Sci U S A 2011 Dec 27;():. Copyright 2011 National Academy of Sciences, U.S.A. J:179977
Associated
Alleles
Symbol Name
Tbx3tm1.1Moon T-box 3; targeted mutation 1.1, Anne M Moon
Tbx3tm2Moon T-box 3; targeted mutation 2, Anne M Moon
Associated
Genotypes
Allelic Composition Genetic Background
Tbx3tm1.1Moon/Tbx3tm2Moon involves: 129 * C57BL/6 * SJL
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory