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Phenotype Image Detail
Image
Caption P3h2tm1Hpb/P3h2tm1Hpb (P3H2 null) and normal littermates at 6.5 d postconception. (A and B) Isolated embryos at E6.5. Both embryos appear morphologically normal. Arrowheads are pointing to the maternal blood neighboring embryos. There is a blood clot in close proximity to the embryo seen in B. Representative sections of normal and mutant E6 deciduae are shown unstained (C and D) and stained with the Wright's stain (E and F). Arrowheads indicate maternal blood invading the ectoplacental cone. Thrombus formation next to the mutant embryo (E) is observed in D and F. Wright's stain visualizes maternal platelets in purple (F, arrowhead). Note that erythrocytes appear orange to pink and are difficult to differentiate from the purple platelets. (Scale bars: A and B, 200 um; C-F, 100 um.)
Copyright This image is from Pokidysheva E, Proc Natl Acad Sci U S A 2014 Jan 7;111(1):161-6. Copyright 2014 National Academy of Sciences, U.S.A. J:206377
Associated
Alleles
Symbol Name
P3h2tm1Hpb prolyl 3-hydroxylase 2; targeted mutation 1, Hans Peter Bachinger
Associated
Genotypes
Allelic Composition Genetic Background
P3h2tm1Hpb/P3h2tm1Hpb involves: 129 * C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory