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Phenotype Image Detail
Image
Caption Scanning electron microscopy images of the aortic valve of a wild-type (WT) littermate (left) and a Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi (XS homo) homozygote with aortic valvular stenosis (right). Note marked thickening of the valve leaflets of the mutant.
Copyright This image is from Kelsey L, PLoS Genet 2013;9(7):e1003612, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:206507
Associated
Alleles
Symbol Name
Klf3Gt(XS0187)Wtsi Kruppel-like transcription factor 3 (basic); gene trap XS0187, Wellcome Trust Sanger Institute
Associated
Genotypes
Allelic Composition Genetic Background
Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi involves: 129P2/OlaHsd * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory