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Phenotype Image Detail
Image
Caption Skeletal defects in Hat1tm1.1Mrpa/Hat1tm1.1Mrpa (Hat1-/-) mice. A) Micro CT scans of the heads of neonates with the indicated genotype. Top row shows a dorsal view and bottom row shows a ventral view. Arrows indicate defects in the nasal cavity (top) and jaw structures (bottom). B) Micro CT scans of wild-type (WT) and mutant neonates (as indicated) showing a dorsal view of the entire animal. C) Acian blue and Alizarin red stained WT and mutant neonates. D) WT and mutant embryos (12.5 dpc) were stained with anti-Hat1 antibodies. E) Cross section of the head and neck of 11.5 dpc WT and mutant embryos stained with alpha-Hat1 antibody. 2.5x magnification.
Copyright This image is from Nagarajan P, PLoS Genet 2013 Jun;9(6):e1003518, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:199077
Associated
Alleles
Symbol Name
Hat1tm1.1Mrpa histone aminotransferase 1; targeted mutation 1.1, Mark R Parthun
Associated
Genotypes
Allelic Composition Genetic Background
Hat1tm1.1Mrpa/Hat1tm1.1Mrpa involves: C57BL/6J

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory