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Phenotype Image Detail
Image
Caption Advanced skeletal muscle development in Capn6tm1Hiso/Capn6tm1Hiso (Capn6lacZ/lacZ) embryos. (A-D) X-gal-stained coronal sections of the tongue of an E16.5 Capn6tm1Hiso/Capn6+ (Het) (A, C) and Capn6tm1Hiso/Capn6tm1Hiso (Ho) (B, D) embryo. The boxed areas in A and B are enlarged in C and D, respectively. Scale bar: 50 um. (E) The average diameter of tongue muscle fibers was measured in the anterior region of coronal sections. The average diameter was significantly larger in homozygotes (9.13 [mean] +/-0.56 [s.e.m.] um, n = 5) than in heterozygotes (5.64 +/- 0.23 um, n = 5). **, P < 0.01 by Student's t-test.
Copyright This image is from Tonami K, PLoS Genet 2013 Aug;9(8):e1003668, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:200747
Associated
Alleles
Symbol Name
Capn6tm1Hiso calpain 6; targeted mutation 1, Hiroyuki Sorimachi
Associated
Genotypes
Allelic Composition Genetic Background
Capn6tm1Hiso/Capn6tm1Hiso B6.Cg-Capn6tm1Hiso

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory