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Phenotype Image Detail
Image
Caption Lens induction failure in Pax6tm2(Pax6_i5a,Pax2)Xzh/Pax6tm2(Pax6_i5a,Pax2)Xzh (Pax65a/5a) and Pax6tm2.1(Pax6_i5a,Pax2)Xzh/Pax6tm2.1(Pax6_i5a,Pax2)Xzh (Pax6Pax2/Pax2) knock-in mutants. A-C, no obvious eye structure was observed in the E15.5 mutants (arrows).
Copyright This image is from Carbe C, J Biol Chem 2013 Apr 26;288(17):12130-41 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:198381
Associated
Alleles
Symbol Name
Pax6tm2.1(Pax6_i5a,Pax2)Xzh paired box 6; targeted mutation 2.1, Xin Zhang
Pax6tm2(Pax6_i5a,Pax2)Xzh paired box 6; targeted mutation 2, Xin Zhang
Associated
Genotypes
Allelic Composition Genetic Background
Pax6tm2(Pax6_i5a,Pax2)Xzh/Pax6tm2(Pax6_i5a,Pax2)Xzh involves: 129S6/SvEvTac
Pax6tm2.1(Pax6_i5a,Pax2)Xzh/Pax6tm2.1(Pax6_i5a,Pax2)Xzh involves: 129S6/SvEvTac * C57BL/6 * FVB/N

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory