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Phenotype Image Detail
Image
Caption Colon tumors induced by azoxymethane/dextrate sulfate sodium salt (AOM/DSS) treatment. Neu3tm1Yamk/Neu3tm1Yamk (KO) or wild-type (wild) mice were subjected to a single AOM injection followed by DSS administration in the drinking water. Colons were dissected 20 weeks after AOM injection and fixed with formalin. A. Macroscopic photograph of dissected colons. Tumors developed at the distal ends of colons are indicated by arrowheads for easy recognition. B. Micrographs of the colon adenocarcinoma. Representative examples of adenocarcinomas developed in the mutant (left) or in the wild-type (right) mouse. Sections from paraffin-embedded tumors were stained with hematoxylin and eosin by standard techniques. Bars, 0.1 mm.
Copyright This image is from Yamaguchi K, PLoS One 2012;7(7):e41132, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:189604
Associated
Alleles
Symbol Name
Neu3tm1Yamk neuraminidase 3; targeted mutation 1, Kazunori Yamaguchi
Associated
Genotypes
Allelic Composition Genetic Background
Neu3tm1Yamk/Neu3tm1Yamk B6.129-Neu3tm1Yamk

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory