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| Caption | Primary fibroblasts were processed for immunofluorescence on experimental day 5, as shown in Fig. 2A. (A) Example of metaphase in a control cell (NuMA +/+ ) and two Numa1tm1.1Dwc/Numa1tm1.1Dwc Tg(CAG-cre/Esr1*)5Amc/0 (NuMA delta22/delta22 ) primary fibroblasts. Arrows indicate centrosomes. (B) Anaphase in wild-type and two mutant primary cells. Each image represents a maximum intensity projection of a deconvolved series of z sections spanning the entire cell in 0.2-um intervals. Arrows indicate centrosomes. Tubulin is shown in green, and phosphorylated histone H3 is shown in purple. | ||||||
| Copyright | This image is from Silk AD, J Cell Biol 2009 Mar 9;184(5):677-90, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:146214 | ||||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/09/2024 MGI 6.23 |
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