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Phenotype Image Detail
Image
Caption Cardiac structure in Adra2btm1Gsb/Adra2btm1Gsb (Adra2b-/-)) mice on postnatal day 0. h and i, frontal sections through hearts on day P0 revealed normal cardiac structure (hematoxylin and eosin staining; bars, 500 um) and closure of the ductus arteriosus (A, aorta; DA, ductus arteriosus (arrow); LV, left ventricle; RV, right ventricle). However, the right ventricle is significantly dilated.
Copyright This image is from Haubold M, J Biol Chem 2010 Oct 29;285(44):34213-9 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166788
Associated
Alleles
Symbol Name
Adra2btm1Gsb adrenergic receptor, alpha 2b; targeted mutation 1, Gregory S Barsh
Associated
Genotypes
Allelic Composition Genetic Background
Adra2btm1Gsb/Adra2btm1Gsb B6.129-Adra2btm1Gsb

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory