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Phenotype Image Detail
Image
Caption D, quantification of plaque load in the cortex and hippocampus of Apptm3.1Zhe/Apptm3.1Zhe Psen1tm1Mpm/Psen1tm1Mpm (APP/hAbeta/mutC PS1 M146V/M146V), Apptm3.1Zhe/Apptm3.1Zhe Psen1tm1Mpm/App+ (APP/hAbeta/mutC PS1 M146V/+), and Apptm1Ck/Apptm1Ck Psen1tm1Mpm/Psen1tm1Mpm (APP/hAbeta PS1 M146V/M146V) mice. ***, p < 0.001; N.S., non-significant (analysis of variance).
Copyright This image is from Li H, J Biol Chem 2010 Oct 1;285(40):30598-605 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166379
Associated
Alleles
Symbol Name
Apptm3.1Zhe amyloid beta (A4) precursor protein; targeted mutation 3.1, Hui Zheng
Psen1tm1Mpm presenilin 1; targeted mutation 1, Mark P Mattson
Associated
Genotypes
Allelic Composition Genetic Background
Apptm3.1Zhe/Apptm3.1Zhe
Psen1tm1Mpm/Psen1tm1Mpm
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/17/2023
MGI 6.22
The Jackson Laboratory