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Phenotype Image Detail
Image
Caption Histological analysis of Capns1tm1.1Otsu/Capns1tm1.1Otsu Tg(Myh6-cre)2182Mds/0 (Capns1-/-) hearts 7 days after transverse aortic constriction (TAC). A, hematoxylin/eosin-stained heart sections. Scale bars = 25 um. B, cardiomyocyte cross-sectional area measured in the sections in A. Open and closed bars represent sham- and TAC-operated groups, respectively. Values are expressed as the mean +/-S.E. *, p<0.05 versus the corresponding sham-operated group. C, Azan-Mallory stained heart sections. Quantification of fibrotic area is shown in the graph. Scale bars = 100 um. Open and closed bars represent sham- and TAC-operated groups, respectively. Values are expressed as the mean +/-S.E. *, p<0.05 versus all other groups.
Copyright This image is from Taneike M, J Biol Chem 2011 Sep 16;286(37):32170-7 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:176736
Associated
Alleles
Symbol Name
Capns1tm1.1Otsu calpain, small subunit 1; targeted mutation 1.1, Kinya Otsu
Tg(Myh6-cre)2182Mds transgene insertion 2182, Michael D Schneider
Associated
Genotypes
Allelic Composition Genetic Background
Capns1tm1.1Otsu/Capns1tm1.1Otsu
Tg(Myh6-cre)2182Mds/0
involves: C57BL/6J * FVB/N

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory