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Phenotype Image Detail
Image
Caption Differences in islet morphology between Gt(ROSA)26Sortm1(Kcnj11*V59M)Fmas/Gt(ROSA)26Sor+ Tg(Ins2-cre)23Herr/0 (BetaV59M), wild-type (WT), Tg(Ins2-cre)23Herr/0 (RIP-Cre) and Gt(ROSA)26Sortm1(Kcnj11*V59M)Fmas/Gt(ROSA)26Sor+ (ROSA) mice. A. Representative sections of mouse pancreas, to illustrate the differences in islet morphology. Sections were stained for insulin using 3,3'-diaminobenzidine (DAB; thus beta-cells appear brown) and counterstained with haematoxylin. Scale bar = 100 um.
Copyright This image is from Girard CA, J Clin Invest 2009 Jan;119(1):80-90 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:144715
Associated
Alleles
Symbol Name
Gt(ROSA)26Sortm1(Kcnj11*V59M)Fmas gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Frances M Ashcroft
Tg(Ins2-cre)23Herr transgene insertion 23, Pedro Luis Herrera
Associated
Genotypes
Allelic Composition Genetic Background
Gt(ROSA)26Sortm1(Kcnj11*V59M)Fmas/Gt(ROSA)26Sor+
Tg(Ins2-cre)23Herr/0
involves: 129S4/SvJae * C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory