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| Caption | At 8 weeks of age wild-type (WT) mice exhibit clear lenses (A) in contrast to total cataracts observed in Srebf2lop13/Srebf2lop13 eyes (B). Histological analysis of lens sections from WT lenses (C) revealed highly organized fiber cells while swollen fiber cells (arrow) and bladder cells (arrowhead) were identified in mutant lenses (D). At the posterior of the mutant lenses (F) morgagnian globules and liquefied lens material (asterisk) were noted. Clear and organized lens structures were observed in WT lenses (E). | ||||
| Copyright | This image is from Merath KM, Mamm Genome 2011 Aug 21;(): and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:176249 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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