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| Caption | Mapk6tm1Melo/Mapk6tm1Melo mice display neonatal lethality. (A) Representative photograph of a cyanotic Mapk6tm1Melo/Mapk6tm1Melo pup (-/-) and wild-type (+/+) littermate immediately after birth. (B) Lungs isolated from a wild-type newborn are well inflated as compared to those of a mutant mouse. (C) Mutant newborns surviving acute respiratory failure lack milk (*) in their stomach. Note the carpoptosis (arrow) in the mutant mouse. (D) Body weight distribution of wild-type, heterozygous and mutant newborns after birth. The mean body weight is indicated for each genotype. | ||||
| Copyright | This image is from Klinger S, Proc Natl Acad Sci U S A 2009 Sep 29;106(39):16710-5. Copyright 2009 National Academy of Sciences, U.S.A. J:153218 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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