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Phenotype Image Detail
Image
Caption Analysis of neural tube closure. A: Wild-type (+/+) and Atp2c1tm1Ges/Atp2c1tm1Ges (-/-) embryos from the same litter at ED 10.5. The neural tube (white arrows) is closed in the wild-type but open in the mutant. Note the appearance of the neuroectoderm in the area of the rhombencephalon, which is ruffled in the mutant (red arrow). B: Hematoxylin & eosin stained sections of wild-type and mutant embryos at ED 9.5, fixed in utero. The neural tube is closed in the wild-type and open in the mutant, which also exhibits ruffling of the neuroectoderm (red arrow). N, neuroectoderm; M, mesenchyme. Bar, 100 um.
Copyright This image is from Okunade GW, J Biol Chem 2007 Sep 7;282(36):26517-27 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:124662
Associated
Alleles
Symbol Name
Atp2c1tm1Ges ATPase, Ca++-sequestering; targeted mutation 1, Gary E Shull
Associated
Genotypes
Allelic Composition Genetic Background
Atp2c1tm1Ges/Atp2c1tm1Ges involves: 129X1/SvJ * Black Swiss

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory