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| Caption | Histological comparison of lungs from wild-type and Man1a2tm1.1Ahe/Man1a2tm1.1Ahe mice. A and B, both wild-type (+/+) and Man1a2tm1.1Ahe/Man1a2tm1.1Ahe (-/-) mice display typical branching at E18.5. However, the interalveolar septae in mutant lungs are thicker than those in wild-type lungs (arrows denote comparable regions). Magnification was x100 (A) and X400 (B). C, alveolar hemorrhaging is observed within the air spaces of mutant lungs (< P0.5, magnification x400). As expected the interalveolar septae of wild-type neonatal lungs are thinner than those observed in E18.5 lungs. However, the interalveolar septae in mutant neonates remain relatively thicker than those in wild-type lungs, as indicated by arrows. Hematoxylin and eosin stained sections are shown. | ||||
| Copyright | This image is from Tremblay LO, J Biol Chem 2007 Jan 26;282(4):2558-66 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:119977 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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