About   Help   FAQ
Phenotype Image Detail
Image
Caption Histological analysis of 8 day old wild-type and PisdGt1(Betageo)Jev/PisdGt1(Betageo)Jev embryos. Sagittal sections were made from embryos with surrounding deciduas. Tissues were fixed, embedded in paraffin, and serial sections were stained with hematoxylin/eosin. Size bars in A and C represent 500 nm, whereas for B and D size bars represent 200 nm. A and B, wild-type embryo. C and D, PisdGt1(Betageo)Jev/PisdGt1(Betageo)Jev embryo. A and C show overview of embryos with surrounding deciduas (Dc), placenta (P), and somites (S). B, detailed view of wild-type embryo that has developed the ectoderm (Ec), mesoderm (M), endoderm (En), and the amnion (Am). The extra-embryonic component is clearly defined. D, in mutant embryos, no differentiation of the three germ layers was observed. The extra-embryonic component is absent, and blood cells (indicated by asterisks) directly surround the embryo.
Copyright This image is from Steenbergen R, J Biol Chem 2005 Dec 2;280(48):40032-40 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:104104
Associated
Alleles
Symbol Name
PisdGt1(Betageo)Jev phosphatidylserine decarboxylase; gene trap 1, Jean E Vance
Associated
Genotypes
Allelic Composition Genetic Background
PisdGt1(Betageo)Jev/PisdGt1(Betageo)Jev involves: 129S2/SvPas * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/30/2024
MGI 6.23
The Jackson Laboratory