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| Caption | Development of cataract in Pcbd1tm1Grc/Pcbd1tm1Grc mice. A: Pcbd1tm1Grc/Pcbd1tm1Grc (DCoH -/-) mouse showing unilateral lens opacity. B: Plot displaying the frequency of first visual observation of cataract in mutant mice in age intervals up to 1 year. C: Section of a mutant mouse with posterior cortical cataract (right) and a Pcbd1tm1Grc/Pcbd1+ mouse of similar age with a healthy eye (left). Transverse sections of paraffin-embedded tissue were stained with hematoxylin and eosin. Note the vacuoles visible in the iris and the Morgagnian granules of degraded and fluid filled lens tissue underlying the posterior capsule. | ||||
| Copyright | This image is from Bayle JH, J Biol Chem 2002 Aug 9;277(32):28884-91 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:78257 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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