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| Caption | Mammary gland analysis in virgin female mice. Red carmine whole-mount staining (A-C) and hematoxylin and eosin staining of paraffin sections (D-F) of mammary glands of wild-type (+/+, A and D), Hrastm2Xbr/Hras1+ (+/G12V, B and E), and Hrastm2Xbr/Hrastm2Xbr (G12V/G12V, C and F) mice. Insets show representative detail. Mammary glands of homozygous mutant mice displayed substantial white fat atrophy, greater ductal-lobulillar development (arrowheads), and ductal ectasia (asterisk). Scale bars: 1 mm (A-C); 10 um (D-F). | ||||
| Copyright | This image is from Schuhmacher AJ, J Clin Invest 2008 Jun;118(6):2169-79 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:137729 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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