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| Caption | Light microscopy of thoracic aortas in wild-type (+/+) and Loxtm1Ikh/Loxtm1Ikh (-/-) mice. Serial sections of thoracic aortas (x400) are displayed. The upper two panels represent hematoxylin and eosin (H&E) stained sections. Note the disrupted smooth muscle cells in mutant, but not wild-type mice (arrows). The middle panels stained with trichrome demonstrate discontinuity of collagen in mutant, but not wild-type mice (arrows). Lower panel, photomicrographs of tissue sections stained with Hart's elastin stain. The arrows highlight a well developed internal elastic lamina and concentric lamellae in wild-type mice, whereas it is fragmented and discontinuous in mutant mice (arrows). | ||||
| Copyright | This image is from Hornstra IK, J Biol Chem 2003 Apr 18;278(16):14387-93 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:82926 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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