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Phenotype Image Detail
Image
Caption Radiographs of 30 day old wild type (wt) and Tnfsf11tm1Ywc/Tnfsf11tm1Ywc (ko) mice. Top row shows hind limb, pelvis and vertebrae. Insets show higher magnification of the proximal tibia. (Lower) Skulls hemisected in the midline. Marrow cavities are absent in the osteopetrotic mutant mouse. The cartilage growth plate, seen as a radiolucent stripe across the proximal tibia in the mutant mouse (arrow) is thicker in the mutant mouse. Incisors, evident in the wild type, fail to erupt in the mutant (arrowhead), as do the molars.
Copyright This image is from Kim N, Proc Natl Acad Sci U S A 2000 Sep 26;97(20):10905-10. Copyright 2000 National Academy of Sciences, U.S.A. J:64737
Associated
Alleles
Symbol Name
Tnfsf11tm1Ywc tumor necrosis factor (ligand) superfamily, member 11; targeted mutation 1, Yongwon Choi
Associated
Genotypes
Allelic Composition Genetic Background
Tnfsf11tm1Ywc/Tnfsf11tm1Ywc involves: 129P2/OlaHsd

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory