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| Caption | A: Radiograph of the whole body of 2 month old wild type (+/+) and Lrp5tm1Kry/Lrp5tm1Kry (-/-) mice showing decreased lucency of the entire mutant skeleton. B: Histological analysis of vertebrae from 2 month old wild type and mutant mice showing low bone mass in the mutant. C: Histological analysis of vertebrae from 2 week old wild type and mutant mice showing a decreased number of trabeculae in the primary spongiosa of mutant mice. D: Mutant mice have a lower bone mass throughout life. Green triangle indicates a significantly lower bone mass in Lrp5tm1Kry/Lrp5+ mice. Asterisks indicate a statistically significant difference between two groups of mice (P<0.05). Error bar represent SD. | ||||
| Copyright | This image is from Kato M, J Cell Biol 2002 Apr 15;157(2):303-14, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:75973 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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