About   Help   FAQ
Phenotype Image Detail
Caption Comparable sagittal sections of the hippocampus obtained from adult mice were stained with cresyl violet. The hippocampus proper (HP) and the dentate gyrus (DG) of Lrp8tm1Her/Lrp8+ (Apoer2+/-) mice are normal, whereas a splitting of the pyramidal layers is evident in Pafah1b1tm1Awb/Pafah1b1+ (Pafah1b1+/-) and in Lrp8tm1Her/Lrp8tm1Her (Apoer2-/-) mice. Severe dyslamination of cellular layers in seen in Lrp8tm1Her/Lrp8tm1Her Pafah1b1tm1Awb/Pafah1b1+ mice.
Copyright This image is from Zhang G, PLoS ONE 2007;2(2):e252, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:129338
Symbol Name
Lrp8tm1Her low density lipoprotein receptor-related protein 8, apolipoprotein e receptor; targeted mutation 1, Joachim Herz
Pafah1b1tm1Awb platelet-activating factor acetylhydrolase, isoform 1b, subunit 1; targeted mutation 1, Anthony Wynshaw-Boris
Allelic Composition Genetic Background
Pafah1b1tm1Awb/Pafah1b1+ involves: 129S6/SvEvTac
involves: 129S6/SvEvTac * C57BL/6
Lrp8tm1Her/Lrp8tm1Her involves: 129S6/SvEvTac * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
MGI 6.22
The Jackson Laboratory