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Phenotype Image Detail
Image
Caption Prex1tm1Hcew/Prex1tm1Hcew Prex2Gt(RRD186)Byg/Prex2Gt(RRD186)Byg (DKo, right) mice tended to clasp hind legs instead of showing normal escape posture (wild type (WT), left) when lifted by the tail.
Copyright This image is from Donald S, Proc Natl Acad Sci U S A 2008 Mar 18;105(11):4483-8. Copyright 2008 National Academy of Sciences, U.S.A. J:133335
Associated
Alleles
Symbol Name
Prex1tm1Hcew phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1; targeted mutation 1, Heidi C E Welch
Prex2Gt(RRD186)Byg phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2; gene trap RRD186, BayGenomics
Associated
Genotypes
Allelic Composition Genetic Background
Prex1tm1Hcew/Prex1tm1Hcew
Prex2Gt(RRD186)Byg/Prex2Gt(RRD186)Byg 		involves: 129P2/OlaHsd * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory