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| Caption | A-D: Compared with controls (A), Dlg1tm1Jhm/Dlg1tm1Jhm kidneys are small (B), and exhibit severely shortened ureters and hydronephrosis (C and D). The arrow in D points to a dilated ureter and hydronephrotic kidney. E: Unilateral renal agenesis in a mutant embryo from a different litter; arrow in E points to the uterus. F and G: Hematoxylin and eosin staining of coronal sections of E18.5 kidneys; arrow in G points to dilated collecting ducts in the medulla. H and I: Hematoxylin and eosin staining of parasagittal sections of E18.5 kidneys shows eroded parenchyma in the mutant caused by hydronephrosis (I). Scale bars: A-E, 2mm, F-I: 5mm. | ||||
| Copyright | This image is from Mahoney ZX, Proc Natl Acad Sci U S A 2006 Dec 26;103(52):19872-7. Copyright 2006 National Academy of Sciences, U.S.A. J:118250 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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