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Phenotype Image Detail
Image
Caption A & C: Localization of Ptx3 expression in the ventral midbrain (arrow) of wild type neonate. B & D: Ptx3 staining is almost depleted in the Nr4a2tm1Omc/Nr4a2tm1Omc midbrain. TUNEL staining in the ventral midbrain region of wild type (E) and mutant mice (F). Notice the increase in TUNEL positive nuclei (arrowheads) and dying cells (asterisk) in the mutant mice. Scale bar: 20um
Copyright This image is from Saucedo-Cardenas O, Proc Natl Acad Sci U S A 1998 Mar 31;95(7):4013-8. Copyright 1998 National Academy of Sciences, U.S.A. J:46856
Associated
Alleles
Symbol Name
Nr4a2tm1Omc nuclear receptor subfamily 4, group A, member 2; targeted mutation 1, Orla M Conneely
Associated
Genotypes
Allelic Composition Genetic Background
Nr4a2tm1Omc/Nr4a2tm1Omc involves: 129S7/SvEvBrd * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory