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| Caption | Electron micrographs from wild type (A) and Actn4tm1.1Mrpk/Actn4tm1.1Mrpk mice (B-D). As shown, homozygous mutant mice were found to have abnormalities that were typically focal, with some areas of podocyte foot process effacement (B), as well as areas that appeared essentially normal (C). Bottom image (D using tannic acid counterstaining) illustrates electron-dense deposits observed in several podocyte cell bodies in mutant mice. No such deposits were observed in wild type or heterozygous mice. | ||||
| Copyright | This image is from Yao J, PLoS Biol 2004 Jun;2(6):787-94, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:90755 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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