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Phenotype Image Detail
Image
Caption A: Hematoxylin/eosin stained sections of testes from wild type (left) and Spem1tm1Wyan/Spem1tm1Wyan (right) mice. Both show robust spematogenesis, B: Phase-contrast microscopic analyses of wild type and homozygous mutant epididymal sperm. Note that cytoplasmic droplets (CD's) (arrows) are present in the middle piece or the junction between the middle and principal pieces of athe tail in wild type epididymal sperm, whereas mutant mouse epididymal sperm show no CD's. C: Hematoxylin/eosin stained sperm smear preparations. (center and right) Mutant mouse sperm display deformation with heads bent backward pointing to tail tips (arrows) or bent heads wrapped around by necks and middle pieces of the tails (arrowheads). Scale bars: A: 50um; B: 20um; C: 10um
Copyright This image is from Zheng H, Proc Natl Acad Sci U S A 2007 Apr 17;104(16):6852-7. Copyright 2007 National Academy of Sciences, U.S.A. J:120937
Associated
Alleles
Symbol Name
Spem1tm1Wyan spermatid maturation 1; targeted mutation 1, Wei Yan
Associated
Genotypes
Allelic Composition Genetic Background
Spem1tm1Wyan/Spem1tm1Wyan involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory