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Phenotype Image Detail
Image
Caption A-C: Normal control mouse (A), CasrNuf/Casr+ mouse with few nuclear flecks (B), and CasrNuf/CasrNuf mouse with more and larger flecks (C). D-J: Soft tissue mineralization in homozygous mutant mice. Arrows indicate sites of mineralization. D: Faxitron x-ray image of a fixed tongue. E-J: hematoxylin and eosin stained sections of the tongue (E), colon (F), skin vibrissa dermal sheath (G), testis artery wall (H), and blood vessels (I) in kidney cortex. J: Positive Von Kossa staining confirms a calcium component of the mineralized deposits in the renal blood vessels.
Copyright This image is from Hough TA, Proc Natl Acad Sci U S A 2004 Sep 14;101(37):13566-71. Copyright 2004 National Academy of Sciences, U.S.A. J:92612
Associated
Alleles
Symbol Name
CasrNuf calcium-sensing receptor; nuclear flecks
Associated
Genotypes
Allelic Composition Genetic Background
CasrNuf/CasrNuf involves: 102/El * C3H/He
CasrNuf/Casr+ either: (involves: 102/El * 102/H * C3H/He) or (involves: 102/El * C3H/He * C3H/HeH)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory