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| Caption | A-C: Eyes of adult wild type (left), Pax6tm1Gfs/Pax6+ (center), and Pax6tm1Gfs/Pax6tm1Gfs (right) mice. Both heterozygous and homozygous mice have hypoplasia of the iris with a larger pupil (arrows) relative to the wild type mouse. D: Whole mount view of the eyes of adult mice after fixation. The iris is the black area and the lens is white. Both heterozygous and homozygous eyes have iris hypoplasia (arrows). E & F: Close up view of a homozygous mouse eye (F) showing an irregular iris (arrow) in the pupil region compared with the regular and smooth iris of a wild type mouse (E). Magnifications: A-C: x20; D: x40; E & F: x60 | ||||||
| Copyright | This image is from Singh S, Proc Natl Acad Sci U S A 2002 May 14;99(10):6812-5. Copyright 2002 National Academy of Sciences, U.S.A. J:76576 | ||||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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