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| Caption | Hematoxylin and eosin stained sagittal brain sections from a 6 month old wild type and age matched Ppt1tm1Hof/Ppt1tm1Hof mouse. A: Homozygous mutant mouse hippocampus showing ballooning degeneration and loss of neurons. Large arrows denote ballooning of neurons; small arrows show neuronal apoptotic bodies. B: Homozygous mutant mouse Purkinje neurons in the cerebellum show neuronal loss, resulting in a discontinuous Purkinje layer. C: Wild-type hippocampal region. D: Wild-type Purkinje neurons of the cerebellum. Scalebar: 40um | ||||
| Copyright | This image is from Gupta P, Proc Natl Acad Sci U S A 2001 Nov 20;98(24):13566-71. Copyright 2001 National Academy of Sciences, U.S.A. J:72931 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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