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Phenotype Image Detail
Image
Caption A-F: Cerebellar sections from wild-type (a & d), Foxp2tm1Bux/Foxp2+ (b & e). and Foxp2tm1Bux/Foxp2tm1Bux mice (c & f). G-I: Immunostaining for calbindin (green) in brains of wild-type (g). heterozygous mice (g), and homozygous mice (i). J-L: Immunostaining for GFAP (red) in brains of wild-type (j), heterozygous (k) and homozygous mice (l). The sections in G-L are also stained with a DAPI nuclear stain (blue). Abbreviations: granule cell layer (gcl); Purkinje cell layer (pcl);m molecular layer (ml); external granular layer (egl). Scalebar: 50um
Copyright This image is from Shu W, Proc Natl Acad Sci U S A 2005 Jul 5;102(27):9643-8. Copyright 2005 National Academy of Sciences, U.S.A. J:99864
Associated
Alleles
Symbol Name
Foxp2tm1Bux forkhead box P2; targeted mutation 1, Joseph D Buxbaum
Associated
Genotypes
Allelic Composition Genetic Background
Foxp2tm1Bux/Foxp2tm1Bux involves: C57BL/6
Foxp2tm1Bux/Foxp2+ involves: C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory