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Phenotype Image Detail
Image
Caption C: At 7 weeks of age the Chrna3tm1Bay/Chrna3tm1Bay mouse (left) is smaller and eyes are closed, compared to the +/+ littermate mouse (right). D & E: Eye comparison shows the larger globe and tiny pupil of the +/+ littermate mouse (left) and the smaller eye and very widely dilated pupil of the Chrna3tm1Bay/Chrna3tm1Bay mouse (arrowheads indicate margins of pupils). F: The bladder from a +/+ mouse (center) is compared with two bladders from Chrna3tm1Bay/Chrna3tm1Bay mice, the left contains clear urine and the right contains cloudy urine. G: Bladder from a Chrna3tm1Bay/Chrna3tm1Bay mouse that has been partially cut to demonstrate the dense stone formation filling the bladder.
Copyright This image is from Xu W, Proc Natl Acad Sci U S A 1999 May 11;96(10):5746-51. Copyright 1999 National Academy of Sciences, U.S.A. J:54994
Associated
Alleles
Symbol Name
Chrna3tm1Bay cholinergic receptor, nicotinic, alpha polypeptide 3; targeted mutation 1, Baylor College of Medicine
Associated
Genotypes
Allelic Composition Genetic Background
Chrna3tm1Bay/Chrna3tm1Bay involves: 129S7/SvEvBrd * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory