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| Caption | Generation of the Icostm1Wks [Icos (y181f)-Neo] and Icostm1.1Wks [Icos(y181f)] alleles. The targeting vector was constructed with Neo cassette flanked by two loxP elements for positive selection and DT-A for negative selection. The exon 4 containing Tyr-181 residue is represented with a filled box, the Southern blot probes are denoted with thick underlines, and PCR primers are shown as arrow heads. | ||||||
| Copyright | This image is from Gigoux M, Proc Natl Acad Sci U S A 2009 Dec 1;106(48):20371-6. Copyright 2009 National Academy of Sciences, U.S.A. J:155586 | ||||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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