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| Caption | Generation of the Kcnq5tm1.1Tjj allele. Scheme of mouse genomic wild-type Kcnq5 sequence (C) and mouse genomic dominant-negative Kcnq5 sequence (D). A NEO selection cassette flanked by loxP sites was introduced into intron 5, together with three point mutations in exon 6 that replace glycine 278 by serine and additionally generate a BsiWI restriction site. The NEO cassette was removed by Cre-recombinase in vitro (exons shown in red). | ||||
| Copyright | This image is from Tzingounis AV, Proc Natl Acad Sci U S A 2010 Jun 1;107(22):10232-7. Copyright 2010 National Academy of Sciences, U.S.A. J:195336 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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