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| Caption | Generation of the Gli2tm3.1Blnw allele that expresses a GLI2 protein lacking sumoylation sites at both Lys-630 and Lys-716. A, the gene targeting strategy used to create the allele and screen for mutant ES cell clones. Open rectangles are referred to as exons, and two lysines (K) indicate the SUMO sites, which were mutated to arginines (RR) in the mutant. PKA sites are indicated. The relevant restriction sites are: B, BamHI; Bg, BglII; Bs, BstZ171; E, EcoRI; Sp, SpeI. | ||||
| Copyright | This image is from Han L, J Biol Chem 2012 Jun 8;287(24):20483-9 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:186503 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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