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| Caption | Generation of Sdhdtm1Jpb allele. Schematic diagram of the strategy used to target the mouse Sdhd locus. The structure of the endogenous murine gene is shown in the middle with the targeting vector above and the disrupted allele below. Genomic DNA is represented by narrow horizontal lines with exons (shaded boxes), orientation of transcription (arrows), translation initiation and stop codons indicated; Genomic sequences flanking the betaGeo selection-reporter cassette (open box) in the targeting vector are represented by broad lines. Primers for genotyping (small arrows) and RT-PCR (arrowheads) are indicated below and above their target sequences, respectively. The dumbbells indicate the location of Southern blot probes used. | ||||
| Copyright | This image is from Bayley JP, PLoS One 2009;4(11):e7987, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:155380 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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