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Caption Generation of the Erbb3tm1.1Dwt allele. (A) Targeted ES cells containing TK-Neo flanked by lox71 (open symbols) and loxP (filled symbols) were transfected with a Cre expression vector to generate the Erbb3 null allele without exon 2. A fragment upstream of 5' homology was used as a probe for Southern blots. The primers (arrowheads) were used for PCR to discern the Erbb3 wild-type (WT) and mutant (null) alleles.
Copyright This image is from Lee D, J Clin Invest 2009 Sep;119(9):2702-13 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:152703
Associated
Alleles
Symbol Name
Erbb3tm1.1Dwt erb-b2 receptor tyrosine kinase 3; targeted mutation 1.1, David Threadgill

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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory