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| Caption | Generation of the Lrrc8atm1.1Geha allele. Structure of the wild-type Lrrc8a allele, the targeting construct, the targeted allele that has undergone homologous recombination before and after Cre-mediated removal of the neo gene, which generates the Lrrc8atm1.1Geha allele. Lrrc8a exons are represented by blue boxes. neo = neomycin resistance gene, tk = thymidine kinase gene. The external 5' and 3' probes are indicated by the bars. The PCR primers used are indicated by the arrows. | ||||
| Copyright | This image is from Kumar L, J Exp Med 2014 May 5;211(5):929-42, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:211308 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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