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| Caption | Generation of the Del(15Krt7-Krt18)1Tmm deletion. 5'-targeting vector (MHPN117k13; Adams et al., 2004). (C) 3'-targeting vector (MHPP322c09; Adams et al., 2004). Gaps [GR] are introduced into the region of homology before targeting. (D) During homologous recombination, the gap is repaired. PCR primers to identify homologous recombinants spanned the gap and the proximal vector sequences. (E) Cre-mediated recombination between loxP sites in cis leading to deletion of the keratin cluster. Southern probes are indicated as bold bars in B-E. | ||||
| Copyright | This image is from Vijayaraj P, J Cell Biol 2009 Oct 19;187(2):175-84, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:153804 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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