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| Caption | Generation of the Kpna6tm1Bdr (importin alpha7deltaIBB) allele. a, Gene targeting strategy. After homologous recombination, exon 2 is replaced by a neomycin resistence (neor) cassette with a polyadenylation site (pA). Since transcription does not always stop at pA, a splicing variant is sometimes generated, carrying an in frame translational start site in exon 3. The sequence of this variant is shown in the lower panels. | ||||
| Copyright | This image is from Rother F, PLoS One 2011;6(3):e18310, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:171441 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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