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| Caption | Generation of the Pdx1tm1.1Stof allele. (A) Targeting strategy to replace the codon encoding Ser210 in the mouse Pdx1 locus with a termination codon (asterisk), thereby preventing translation of the C terminus. Schematic shows both exons (black rectangles), the 5' diphtheria toxin A (DTA) gene, and the loxP-flanked 3' neomycin resistance thymidine kinase (NeoR-tk) cassettes (white rectangles). Black arrows indicate the location of genotyping primers. White arrows denote the location of loxP sites. X indicates sites of homologous recombination. | ||||
| Copyright | This image is from Oliver-Krasinski JM, J Clin Invest 2009 Jul;119(7):1888-98 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:152582 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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