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| Caption | Generation of the Atg4bGt(A029E06)Wrst allele. (A) Top: Schematic representation of the wild-type (wt) Atg4b locus, in which the coding exons are depicted as numbered boxes. Bottom: Gene trap vector structure containing a splicing acceptor (SA), a bacterial Beta-galactosidase fused to the neomycin resistance gene (Beta-geo), and a polyadenylation signal (pA). (B) Schematic representation of the WT and mutant loci showing the new BamHI (B1) restriction polymorphism generated by the insertion of the gene trap vector. The DNA probe used for the detection of the mutant allele is shown. | ||||
| Copyright | This image is from Marino G, J Clin Invest 2010 Jul 1;120(7):2331-44 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:163712 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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