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| Caption | Generation of the Cd84tm1Beni allele. (A) Cd84 targeting strategy: This scheme illustrates the detection of wild-type and mutant (targeted) alleles. Upon homologous recombination, the pWH9 cassette containing a neomycin resistance gene disrupts the Cd84 gene. An external probe (EP) recognizes a sequence downstream of 3' arm in intron 2. With the pWH9 cassette, a new BamHI restriction site is introduced, enabling the determination of a wild-type and mutant band by Southern blot analysis. | ||||
| Copyright | This image is from Hofmann S, PLoS One 2014;9(12):e115306, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:225659 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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