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Molecular Image Detail
Image
Caption Generation of the Wsb1tm1Acb allele. Scheme of the mouse Wsb1 gene showing the 2 LoxP sites flanking exons 6 and 7. When the floxed mouse is crossed with a Cre-expressing mouse, exons 6 and 7 are floxed out and a frame stop codon is formed in exon 8 that prevents translation of the SOCS box located in exon 9.
Copyright This image is from Werneck de Castro JP, J Clin Invest 2015 Feb;125(2):769-81 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:220398
Associated
Alleles
Symbol Name
Wsb1tm1Acb WD repeat and SOCS box-containing 1; targeted mutation 1, Antonio C Bianco

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/20/2026
MGI 6.24
The Jackson Laboratory