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| Caption | Generation of the Cxxc5tm1Kych (CXXC5) allele. High bone mass phenotype of homozygous mutant mice. (a) Scheme of CXXC5 knockout by homologous recombination. The upper line represents the structure in the wild-type (WT) mouse chromosome. The lower line represents a gene map of the targeting vector (pPNT-CXXC5) that was used in the generation of the knockout mice. Oblique lines between the two indicate the recombination scheme. After recombination, PGK-Neo was substituted for exon 2, resulting in the knockout. The positions of the forward and reverse primers (FP and RP) for mouse genotyping are indicated. | ||||
| Copyright | This image is from Kim HY, Cell Death Differ 2015 Jun;22(6):912-20 and is displayed with the permission of The Nature Publishing Group who owns the Copyright. J:226604 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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