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| Caption | Generation of the Stk31tm1.1Jw and Stk31tm1.2Jw alleles. Tudor domain of STK31 is not required for spermatogenesis. (A) Targeted disruption of the tudor domain in the Stk31 gene. Mouse Stk31 gene (encoding a protein of 1018 aa) has 24 exons over a 74-kb genomic region on Chr. 6. The targeting strategy is to flox exon 5 and 6 (encoding 84-161 aa), generating the Stk31tm1.1Jw (Stk31 flox) allele. The floxed region was removed by crossing with ActB-Cre mice, generating the Stk31tm1.2Jw (Stk31 mutant 1) allele. | ||||||
| Copyright | This image is from Zhou J, PLoS One 2014;9(2):e89471, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:213823 | ||||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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