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Molecular Image Detail
Image
Caption Generation of Type 2 helper T cell (Th2) locus control region (LCR) mutant allele, Rad50tm4.1Flv (RHS6 KO). Closed boxes represent Rad50 exons, closed triangles represent Cre recombinase loxP sites, arrows indicate approximate positions ofRad50 DNase I hypersensitive sites (RHS). Deleted region in the RHS6 line is indicated by a black bar. LCR, locus control region; Neo, neomycin resistance gene; TK, Thymidine kinase; TV, targeting vector.
Copyright This image is from Williams A, Proc Natl Acad Sci U S A 2013 Apr 23;110(17):6955-60. Copyright 2013 National Academy of Sciences, U.S.A. J:196154
Associated
Alleles
Symbol Name
Rad50tm4.1Flv RAD50 double strand break repair protein; targeted mutation 4.1, Richard A Flavell
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory