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| Caption | Generation of Type 2 helper T cell (Th2) locus control region (LCR) mutant allele, Rad50tm2.1Flv (RSH4,5,7 KO). Closed boxes represent Rad50 exons, closed triangles represent Cre recombinase loxP sites, arrows indicate approximate positions of Rad50 DNase I hypersensitive sites (RHS). Deleted regions in the RHS45 and RHS6 lines are indicated by a black bar. For the RHS457 lines, the deleted regions are the same as that for the RHS45 line in addition to the deleted RHS7 region. LCR, locus control region; Neo, neomycin resistance gene; TK, Thymidine kinase; TV, targeting vector. | ||||
| Copyright | This image is from Williams A, Proc Natl Acad Sci U S A 2013 Apr 23;110(17):6955-60. Copyright 2013 National Academy of Sciences, U.S.A. J:196154 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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